Ketogenesis · reaction 3 of 4

HMG-CoA → Acetoacetate + Acetyl-CoA

HMG-CoA lyase EC 4.1.3.4

Gives back one of the acetyl-CoA and leaves acetoacetate: the first ketone body, now free of coenzyme A and able to go out into the blood.

in depth

Nelson, D. L. & Cox, M. M. (2021). Lehninger. Principios de bioquímica, 8.ª ed., ch. 17

KetogenesisHMG-CoA lyase

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