Glycogenesis · reaction 1 of 4

Glucose 6-phosphate ⇌ Glucose 1-phosphate

Phosphoglucomutase EC 5.4.2.2

Moves the phosphate from the sixth carbon to the first. That change of place is what later allows the sugar to be activated; on the sixth carbon it would be useless.

endergonic
Cytosol

in depth

ΔG°′: 7.3 kJ/mol
Cofactors: Magnesium
Location: Cytosol

Nelson, D. L. & Cox, M. M. (2021). Lehninger. Principios de bioquímica, 8.ª ed., ch. 15

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