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Map of Cholesterol synthesis: 12 reactions drawn as arrows between their metabolites, with what goes in and out at each step.
Cholesterol synthesis
Cytosol · 12 reactions
· 1 in a red ring, regulated
Regulation point of the pathway
CoA
H₂O
CoA
H₂O
CoA
NADPH + H⁺
CoA + NADP+
ATP
ADP
ATP
ADP
ATP
ADP + Pi +
CO₂
PPi
PPi
PPi
PPi
NADPH + H⁺
PPi + NADP+
O₂ + NADPH +
H⁺
H₂O + NADP+
Acetyl-CoA
Acetoacetyl-CoA
HMG-CoA
Mevalonate
Mevalonate 5-phosphate
Mevalonate 5-diphosphate
Isopentenyl diphosphate
Dimethylallyl diphosphate
Geranyl diphosphate
Farnesyl diphosphate
Squalene
2,3-Oxidosqualene
Lanosterol
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