2 Acetyl-CoA ⇌ Acetoacetyl-CoA + Coenzyme A

Bacterial thiolase EC 2.3.1.9

The fiber we cannot digest reaches the colon intact, and there bacteria ferment it down to acetyl-CoA. From here the assembly of butyrate begins, joining two two-carbon molecules.

Extracellular

in depth

ΔG°′: not documented
Location: Extracellular

Nelson, D. L. & Cox, M. M. (2021). Lehninger. Principios de bioquímica, 8.ª ed., ch. 14

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Fiber fermentationBacterial thiolase

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